Diabetes mellitus type 2 is an endocrine disorder that...

Diabetes mellitus type 2 is an endocrine disorder that causes impaired use of carbohydrates while enhancing the use of proteins and lipids. This is called insulin resistance, in which the pancreas cannot make enough insulin to keep blood glucose levels normal, or the body is unable to use what is produced. The impairment causes blood glucose level to rise higher than normal. There is no cure for type 2 diabetes mellitus and it is life threatening when left untreated. Signs and symptoms of this disorder include vision changes, increased thirst, increased hunger, increased frequency of urination, stomach pain, nausea and vomiting, erectile dysfunction, and absences of mentruation. These can occur abruptly, or over a long period of time.†¦show more content†¦Iodine agents administered intravascularly may lead to renal failure. Ace inhibitors can decrease glucose levels and dose adjustments should be made during the administration of this medication. Adverse reactions inc lude nutritional disorders, lactic acidosis, taste disorders, nausea, vomiting and diarrhea, and liver disorders. The implications metformin has on physical therapy treatment include the risk of lactic acidosis. Signs and symptoms that should be monitored for during physical therapy are muscular cramping along with gastrointestinal pain, shortness of breath, hypothermia, and coma. Glyburide is another generic medication used in the management of diabetes mellitus type 2. Two trade names of this drug are DiaBeta and Glynase. The chemical name is 1-[ [p-[2-(5-chloro-o-anisamido) ethyl]phenyl]-sulfonyl]-3-cyclohexylurea. Doses up to 0.75-12 mg/day can be given as a single dose or divided doses. The circulation of the glyburide is that protein binding is extensive and half-life is 10 hours. It is excreted through the renal and biliary system. Glyburide acts as an oral blood glucose lowering drug. The drugs uses include binding and activating the sulfonylurea receptor 1, which causes depolarization. This results in an increase in intracellular calcium in the cells and stimulation of insulin release. Major drug interactions are noted between glyburide andShow MoreRelatedDiabetes : The Common Chronic Disorders1737 Words   |  7 PagesINTRODUCTION: Diabetes is one of the most common chronic disorders in UK [1]. According to Silverman, more than 2.6 million people in UK are diabetic as according to data collected from GP practices and more than 5 million obese people are registered to GP practices. So One in ten people are getting treatment for obesity and one in 20 are getting treatment for diabetes [2]. It is estimated that more than 5% men and more than 4% women in England are found to have diagnosed diabetes. 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